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Mammalian ATG8 proteins maintain autophagosomal membrane integrity through ESCRTs.
Javed R, Jain A, Duque T, Hendrix E, Paddar MA, Khan S, Claude-Taupin A, Jia J, Allers L, Wang F, Mudd M, Timmins G, Lidke K, Rusten TE, Akepati PR, He Y, Reggiori F, Eskelinen EL, Deretic V. Javed R, et al. Among authors: akepati pr. EMBO J. 2023 Jul 17;42(14):e112845. doi: 10.15252/embj.2022112845. Epub 2023 Jun 5. EMBO J. 2023. PMID: 37272163 Free article.
Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity.
Reeves EP, Dunlea DM, McQuillan K, O'Dwyer CA, Carroll TP, Saldova R, Akepati PR, Wormald MR, McElvaney OJ, Shutchaidat V, Henry M, Meleady P, Keenan J, Liberti DC, Kotton DN, Rudd PM, Wilson AA, McElvaney NG. Reeves EP, et al. Among authors: akepati pr. J Immunol. 2019 Apr 15;202(8):2240-2253. doi: 10.4049/jimmunol.1801045. Epub 2019 Feb 22. J Immunol. 2019. PMID: 30796179 Free PMC article. Clinical Trial.
A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics.
Giadone RM, Rosarda JD, Akepati PR, Thomas AC, Boldbaatar B, James MF, Wilson AA, Sanchorawala V, Connors LH, Berk JL, Wiseman RL, Murphy GJ. Giadone RM, et al. Among authors: akepati pr. Amyloid. 2018 Sep;25(3):148-155. doi: 10.1080/13506129.2018.1489228. Epub 2018 Jul 21. Amyloid. 2018. PMID: 30032658 Free PMC article.